The Advanced Cancer
Therapy Foundationis a 501(c)(3) non-profit organization
seeking to improve the treatment of cancer patients through
new, advanced particle beam therapy. The Foundation will
provide funds for highest level research activities in
this exciting and promising new territory. For more information
call: 505-983-7664 or e-mail info@advanced-cancer-therapy.org
What
is particle beam cancer therapy?
Particle beam cancer therapy is a non-invasive method
that utilizes protons, heavy ions, or antiprotons instead
of surgery or x-rays to terminate cancer. Independent of
a specific cancer type it can be used on all tumors with
a defined shape.
What
are the advantages of using particle beams?
Particle beams have the unique capability to deliver energy
to a well defined location in the body with minimal impact
to cells in the beam path in front of the target region,
and with no effect to tissue behind the target region. This
allows treatment of tumors close to critical and radiation
sensitive organs, reducing side effects and the late occurrence
of secondary tumors. Using modern imaging technology, some
types of particles allow detecting the exact location of
treatment from the outside of the patient’s body. For
antiprotons this promises to result in true real-time imaging
during therapy, giving direct feedback to the physician at
time of treatment.
How
does particle beam therapy work?
On
an atomic scale the human body is amazingly empty. A beam
of protons or ions entering the human body will at first deposit
very little energy while continuing its path through this
virtually empty space. Only electrical forces between the
beam particles and the atoms in the human body will slow down
the motion, and eventually the particle will stop. At this
moment the majority of the energy is deposited. Where this
happens can be chosen precisely by changing the initial velocity
of the particles. This is in strong contrast to a beam of
X-rays, where the energy deposited to the human cells is highest
close to the surface, and then continues to decrease until
the exit of the body. Particle beams, in contrast, deposit
only a low dose in the entrance channel, the highest dose
at the target area, and virtually zero dose beyond.
Which particles are used in advanced particle beam cancer
therapy?
Up to now the particle of choice was the proton, the nucleus
of a hydrogen atom. 40+ proton beam therapy centers exist
and have to date treated more than 50,000 patients worldwide.
In recent years research in Germany and in Japan has shown
that carbon ions can have a much higher biological impact
on cancer cells than protons and can therefore successfully
treat tumors normally deemed “radio-resistant”.
Carbon ion treatments have yielded significantly improved
treatment results in many types of tumors. But up to now only
3000 patients have received Carbon ion treatments. Antiprotons,
known to most of us only from science fiction, have already
been shown to offer yet another increase of effective dose
in the target area, have the potential to further decreasing
the impact on healthy tissue in front of the tumor, and additionally
would allow watching in real time where exactly inside the
body the treatment is administered.
Our
Mission?
Despite all the success achieved, particle beam cancer
therapy is still an important and active area of fundamental
research. Much work is still necessary to assure that the
most effective treatment with the lowest achievable side
effects can be offered to each and every specific case.
The Advanced Cancer Therapy Foundation has made it to its
primary goal to foster this work by providing financial
support to scientists committed to making this non-invasive
method of “surgery” available to patients in
the US and the entire World.
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